KRAS G12C inhibitor 14 是一种有效的 KRAS G12C 抑制剂，IC50 为 18 nM，详细信息请参考专利文献 WO2019110751A1 中的化合物 17。
货号:ajcx37622
CAS:2349393-95-7
分子式:C24H19ClF2N4O3
分子量：484.88
溶解度:DMSO : 100 mg/mL (206.24 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 17, has an IC50 of 18 nM[1].

[1]. Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.