GSK854 是一种有效的肌钙蛋白 I 相互作用激酶 (TNNI3K) 抑制剂。GSK854 是一种合适的先导药物，可用于识别新的心脏药物，并已在旨在确定 TNNI3K 在心力衰竭中的作用的研究中用作体内工具。
货号:ajcx37902
CAS:1316059-00-3
分子式:C18H19ClN6O4S2
分子量：482.96
溶解度:DMSO : 250 mg/mL (517.64 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

GSK854 is a potent Inhibitor of Troponin I-Interacting Kinase (TNNI3K). GSK854 is a suitable lead for identifying new cardiac medicines and have been employed as in vivo tools in investigational studies aimed at defining the role of TNNI3K within heart failure[1].

[1]. Philp J, et al. 4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors. J Med Chem. 2018;61(7):3076-3088.