MLK-IN-1 是一种强效的脑渗透特异性 MLK-3 抑制剂，从专利 US20140256733A1 中获得的化合物 68。
货号:ajcx37994
CAS:1627729-62-7
分子式:C23H20N4O3S
分子量：432.49
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1].

MLK-IN-1 (100 nM; pre-treatment 20 mins HIV-1 Tat) promotes continued axonogenesis in the presence of Tat-activated microglia and protects against effects of HIV-Tat in vitro[1].

[1]. Val S. Goodfellow,et al.Mixed lineage kinase inhibitors and method of treatments. Patent US20140256733A1.