MC-Val-Cit-PAB-DX8951 是抗体-药物偶联物的一部分。MC-Val-Cit-PAB-DX8951 由 DNA 拓扑异构酶 I DX-8951 和组织蛋白酶可降解的的 ADC 连接子组成。
货号:ajcx38354
CAS:2504068-28-2
分子式:C53H60FN9O12
分子量：1034.1
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MC-Val-Cit-PAB-DX8951 is a drug-linker conjugate for ADC. MC-Val-Cit-PAB-DX8951 is composed of a DNA topoisomerase I DX-8951 and a cathepsin cleavable ADC linker.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Anish Thomas, et al. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016 Jun;17(6):e254-e262.