(1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) 是一种 BACE1 抑制剂，IC50 分别为 2.2 nM (TR-FRET 测定) 和 0.28 nM (sAPPp 释放测定)，详细信息请参考专利文献 WO2012087237A1 中的化合物 20a。
货号:ajcx14866
CAS:1384082-96-5
分子式:C26H28N4O
分子量：412.53
溶解度:DMSO: 250 mg/mL (606.02 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) is a Beta site APP Cleaving Enzymel (BACE1) inhibitor extracted from patent WO2012087237A1, compound 20a, has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively[1].

[1]. Gabor Csjernyik, et al. Compounds and their use as bace inhibitors. WO2012087237A1.