MC-GGFG-DX8951 是一种抗体-药物偶联物 (drug-linker conjugate for ADC)，具有抗肿瘤活性，由DNA拓扑异构酶 I 抑制剂 DX8951 和蛋白酶可切割的 MC-GGFG 连接而成。
货号:ajcx16392
CAS:1600418-29-8
分子式:C49H51FN8O11
分子量：946.97
溶解度:DMSO: 100 mg/mL (105.60 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker[1].

[1]. Nakada T, et al. Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1542-1545.