Centhaquine (Centhaquin;PMZ-2010) 是一种具有治疗出血性休克的潜力的试剂。Centhaquine (Centhaquin;PMZ-2010) 在出血模型中可以减少全身血管阻力。
货号:ajcx16476
CAS:57961-90-7
分子式:C22H25N3
分子量：331.45
溶解度:DMSO: 62.5 mg/mL (188.57 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Centhaquine (Centhaquin; PMZ-2010) is a novel agent has the potential for treatment of haemorrhagic shock. Centhaquine (Centhaquin; PMZ-2010) can augment cardiac output, reduce systemic vascular resistance in haemorrhagic models[1][2].

[1]. Srimal RC,et al. Pharmacological studies on 2-(2-(4-(3-methylphenyl)-1-piperazinyl)ethyl) quinoline (centhaquin). I. Hypotensive activity.Pharmacol Res. 1990 May-Jun;22(3):319-29. [2]. Papalexopoulou K, et al. Centhaquin Effects in a Swine Model of Ventricular Fibrillation: Centhaquin and Cardiac Arrest.Heart Lung Circ. 2017 Aug;26(8):856-863.