Desmethylnortriptyline 是 Nortriptyline 的代谢产物。Nortriptyline 是三环类抗抑郁药，是 Amitriptyline 的主要活性代谢产物，用于缓解抑郁症症状。
货号:ajcx29278
CAS:4444-42-2
分子式:C18H19N
分子量：249.35
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Desmethylnortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].

[1]. Burch JE, et al. Determination of desmethyl nortriptyline in plasma by gas chromatography before and after treatment with salicylaldehyde. J Chromatogr. 1983 May 13;274:350-4. [2]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.