SGK1-IN-2 (14h) 是一种选择性的 SGK1 (血清和糖皮质激素调节激酶 1) 抑制剂，在 10 μM ATP浓度下 IC50 为 5 nM。
货号:ajcx33708
CAS:1426214-64-3
分子式:C17H12Cl2N6O2S
分子量：435.29
溶解度:DMSO : 62.5 mg/mL (143.58 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

SGK1-IN-2 (14h) is a selective SGK1 (serum and glucocorticoid regulated kinase 1) inhibitor, with an IC50 of 5 nM at 10 μM ATP concentration[1].

[1]. Halland N, et al. Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors. ACS Med Chem Lett. 2014 Oct 23;6(1):73-8.