TAK1-IN-2 是一种有效和选择性的 TAK1 抑制剂，IC50>值为 2 nM。
货号:ajcx33838
CAS:N/A
分子式:C26H26F2N6O5
分子量：540.52
溶解度:DMSO : 10 mg/mL (18.50 mM; ultrasonic and warming and heat to 60°C)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

TAK1-IN-2 is a potent and selective TAK1 inhibitor, with an IC50>of 2 nM[1].

TAK1-IN-2 (compound 54) (10 μM) has no effect on cell viability in TNF-α stimulated HCT-15 cells[1].

[1]. Veerman JJN, et, al. Discovery of 2,4-1 H-Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors. ACS Med Chem Lett. 2021 Mar 3;12(4):555-562.