MRGPRX1 agonist 1 是一种高效的 Mas 相关 G 蛋白偶联受体 X1 (MRGPRX1) 的激动剂，EC50 值为 50 nM，对 MRGPRC11 无活性。MRGPRC11 具有镇痛活性。
货号:ajcx34976
CAS:2377379-39-8
分子式:C23H21N3O4S
分子量：435.5
溶解度:DMSO : 130 mg/mL (298.51 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1), with an EC50 of 50 nM, and is inactive on MRGPRC11. Analgesic effect[1].

[1]. PrchalovÁ E, et al. Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists. J Med Chem. 2019 Sep 26;62(18):8631-8641.