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Acanthoside B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Acanthoside B图片
规格:98%
分子量:580.58
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Acanthoside B 是一种具有抗炎、抗遗忘活性的生物活性木脂素。Acanthoside B 可用于阿尔茨海默病和肺部炎症等疾病的研究。
货号:ajcx36728
CAS:7374-79-0
分子式:C28H36O13
分子量:580.58
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Acanthoside B is a potential bioactive lignan with anti-inflammatory and anti-amnesic activities. Acanthoside B can be used for alzheimer’s disease and lung inflammation research[1]

Acanthoside B (oral gavage; 10-20 mg/kg; 7 days prior to Scopolamine injection) attenuates Scopolamine inflicted AD-like amnesic traits by restoring the cholinergic activity, decreasing the endogenous antioxidant status, suppressing neuroinflammation, and activating the TrkB/CREB/BDNF pathway in mice[1].

[1]. Govindarajan Karthivashan, et al. Cognitive-enhancing and ameliorative effects of acanthoside B in a scopolamine-induced amnesic mouse model through regulation of oxidative/inflammatory/cholinergic systems and activation of the TrkB/CREB/BDNF pathway. Food Chem Toxicol. 2019 Jul;129:444-457.
[2]. Ju Hee Lee, et al. Inhibition of Lung Inflammation by Acanthopanax divaricatus var. Albeofructus and Its Constituents. Biomol Ther (Seoul). 2016 Jan;24(1):67-74.