MP07-66 是一种 FTY720 类似物，没有免疫抑制作用，通过破坏 SET-PP2A 复合物导致 PP2A 重新激活，在慢性淋巴细胞白血病中显示出良好的抗肿瘤作用。
货号:ajcx36834
CAS:1938056-90-6
分子式:C19H33NO3
分子量：323.47
溶解度:DMSO : 250 mg/mL (772.87 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MP07-66, a FTY720 analogue, is devoid of immunosuppressive effects and shows promising antitumor effects in chronic lymphocytic leukemia by disruption of the SET-PP2A complex leading to PP2A reactivation[1].

[1]. Zonta F, et al. Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A. Blood. 2015;125(24):3747-3755.