SR15006 是 Kruppel-like factor 5 (KLF5) 的抑制剂剂 (在 DLD-1 CRC 细胞的中，IC50 = 41.6 nM)。
货号:ajcx37322
CAS:2505001-54-5
分子式:C16H20ClN3O4S
分子量：385.87
溶解度:DMSO : 100 mg/mL (259.15 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

SR15006 is a inhibitor of KrÜppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells)[1].

SR15006 (1 μM or 10 μM; DLD-1 CRC cells) causes a significant reduction in the levels of tested cyclins over the course of 72 hours[1].

[1]. Kim J, et al. The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo. Mol Cancer Ther. 2019;18(11):1973-1984.