BPH-715 是一种二磷酸盐，能够抑制疟原虫肝期生长，在 HepG2 细胞中，抑制疟原虫外红细胞形成，IC50 值为 10 μM。
货号:ajcx39420
CAS:1059677-23-4
分子式:C17H31NO7P2
分子量：423.38
溶解度:0.5 M NaOH : 80 mg/mL (188.96 mM; ultrasonic and adjust pH to 11 with NaOH)|DMSO : 5 mg/mL (11.81 mM; ultrasonic and warming and heat to 60°C)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells[1].

[1]. Singh AP, et al. Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth. Antimicrob Agents Chemother. 2010 Jul;54(7):2987-93.