T16A(inh)-C01 是一种 TMEM16A (ANO1) 抑制剂。T16A(inh)-C01 不干扰钙信号转导，并能阻断TMEM16A 介导的氯离子电流，IC50 为 8.4 μM。
货号:ajcx39518
CAS:171506-87-9
分子式:C18H16O5
分子量：312.32
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling[1].

[1]. Namkung W, et al. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21. 286(3):2365-74.