Pentaethylene glycol di(p-toluenesulfonate) 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
货号:ajcx39666
CAS:41024-91-3
分子式:C24H34O10S2
分子量：546.65
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.