BI-3802是一种高效的BCL6降解剂，能够抑制BCL6的BTB结构域，IC50值≤3nM，具有抗肿瘤活性。
货号:ajcx12760
CAS:2166387-65-9
分子式:C24H29ClN6O3
分子量：484.98
溶解度:DMSO : 5 mg/mL (10.31 mM);Methanol : 2 mg/mL (4.12 mM; ultrasonic and adjust pH to 5 with 1M HCl);H2O :< 0.1 mg/mL (insoluble)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

BI-3802 is a highly potent BCL6 degrader, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3802 has antitumor activity.

BI-3802 is a BCL6 inhibitor, with an IC50 of ≤3 nM. BI-3802 shows an IC50 of 43 nM for the cellular BCL6[1].

[1]. Kerres N, et al. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep. 2017 Sep 19;20(12):2860-2875.