GSK2643943A是一种去泛素化酶(DUB)的抑制剂，其对USP20/Ub-Rho的IC50值为160nM.
货号:ajcx13416
CAS:N/A
分子式:C17H12FN3
分子量：277.3
溶解度:DMSO : ≥ 125 mg/mL (450.78 mM);H2O :< 0.1 mg/mL (insoluble)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC50 of 160 nM for USP20/Ub-Rho.

[1]. "Harrigan JA, et al.Deubiquitylating enzymes and drug discovery: emerging opportunities.Nat Rev Drug Discov. 2018 Jan;17(1):57-78." [2]. Nishi Kumari, et al. Targeting the Ubiquitin Proteasome System in Cancer