(R)-FT671 是 FT671 的 R 型异构体。 FT671是有效、非共价的、选择性的 USP7 抑制剂，IC50 值为 52 nM，与USP7催化域结合的 Kd 值为 65 nM。
货号:ajcx15222
CAS:1959551-27-9
分子式:C24H23F4N7O3
分子量：533.48
溶解度:DMSO: 150 mg/mL (281.17 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(R)-FT671 is the R-isomer of FT671. FT671 is a potent, non-covalent and selective USP7 inhibitor with an IC50 of 52 nM and binds to the USP7 catalytic domain with a Kd of 65 nM[1].

[1]. Turnbull AP, et al. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017 Oct 26;550(7677):481-486.