| 规格: | 98% |
| 分子量: | 349.3 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
Background:
DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2; IC50= 1.6 µM).1It is selective for MTHFD2 over MTHFD1 (IC50= >30 µM).
1.Kawai, J., Ota, M., Ohki, H., et al.Structure-based design and synthesis of an isozyme-selective MTHFD2 inhibitor with a tricyclic coumarin scaffoldACS Med. Chem. Lett.10(6)893-898(2019)
m.cnreagent.com