A biosynthetic precursor to ansamycin antibiotics
货号:ajcx28436
CAS:76045-71-1
分子式:C7H7NO3
分子量：153.1
溶解度:DMF: 1 mg/ml,DMSO: 3 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC₇N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin , as well as the antitumor antibiotic mitomycin C .^1,2

1.Kim, C.-G., Kirschning, A., Bergon, P., et al.Biosynthesis of 3-amino-5-hydroxybenzoic acid, the precursor of mC7N units in ansamycin antibioticsJ. Am. Chem. Soc.118(32)7486-7491(1996) 2.Mao, Y., Varoglu, M., and Sherman, D.H.Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564Chem. Biol.6(4)251-263(1999)