BCL6-IN-4 是一种有效的 B 细胞淋巴瘤 6 (BCL6) 抑制剂，IC50IC50 为 97 nM。BCL6-IN-4 具有抗肿瘤活性。
货号:ajcx34042
CAS:2253879-65-9
分子式:C25H35ClN6O3
分子量：503.04
溶解度:DMSO : 73.33 mg/mL (145.77 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

BCL6-IN-4 is a potent B-cell lymphoma 6 (BCL6) inhibitor with an IC50 of 97 nM. BCL6-IN-4 has anti-tumor activities[1].

BCL6-IN-4 (compound 25b) inhibits OCI-Ly1 and OCI-Ly3 cell lines growth with GI50 values of 2.8 μM and 4.2 μM, respectively[1].

[1]. Benjamin R Bellenie, et al. Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders. J Med Chem. 2020 Apr 23;63(8):4047-4068.