DHODH-IN-17，作为一种 2- 苯胺酰烟酸，是一种人DHODH抑制剂 (IC50=0.40 μM)。DHODH-IN-17 可用于急性髓系白血病 (AML) 的研究。
货号:ajcx35640
CAS:16344-26-6
分子式:C12H9ClN2O2
分子量：248.67
溶解度:DMSO : 100 mg/mL (402.14 mM; ultrasonic and warming and heat to 60°C)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor (IC50=0.40 μM). DHODH-IN-17 can be used for theresearch of acute myeloid leukemia (AML)[1].

DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor with an IC50 value of 0.40 μM[1].

[1]. Lewis TA, et al. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Med Chem Lett. 2016;7(12):1112-1117.