Nimbolide 是一种源自?Azadirachta indica?L 叶和花的三萜化合物。Nimbolide 通过抑制?NF-κB?而诱导肿瘤细胞凋亡。 Nimbolide 抑制?CDK4/CDK6?激酶活性。Nimbolide 抑制 NF-κB，Wnt，PI3K-Akt，MAPK 和 JAK-STAT 信号通路。
货号:ajcx12130
CAS:25990-37-8
分子式:C??H??O?
分子量：466.52
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica?L). Nimbolide induces apoptosis through inactivation of?NF-κB. Nimbolide inhibits?CDK4/CDK6?kinase activity. Nimbolide suppresses the NF-κB, Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways^[1]