Quisinostat dihydrochloride (JNJ-26481585 dihydrochloride) 是一种有口服活性，高效的 pan-HDAC?抑制剂，对 HDAC1，HDAC2，HDAC4，HDAC10，HDAC11 的?IC50?值分别为 0.11 nM，0.33 nM，0.64 nM，0.46 nM 和 0.37 nM。Quisinostat dihydrochloride 具有广泛的抗肿瘤活性。
货号:ajcx12248
CAS:875320-31-3
分子式:C21H28CI12N6O2
分子量：467.39
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Quisinostat dihydrochloride (JNJ-26481585 dihydrochloride) is an orally available, potent pan-HDAC?inhibitor with?IC₅₀s of 0.11 nM, 0.33 nM, 0.64 nM, 0.46 nM, and 0.37 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11, respectively. Quisinostat dihydrochloride has a broad spectrum antitumoral activity^[1].