Phen-DC3是一个G4特异性配体，可以抑制解旋酶FANCJ和DinG且IC50s值分别为65±6和50±10nM。
货号:ajcx12446
CAS:942936-75-6
分子式:C34H26N6O2
分子量：550.61
溶解度:DMSO : ≥ 34 mg/mL (61.75 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.

[1]. Bharti SK, et al. Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem. 2013 Sep 27; 288(39):28217-29.