Telomerase-IN-2 是一种端粒酶 (telomerase) 抑制剂，通过降低角化不良蛋白的表达来抑制其活性，IC50 值为 0.89 µM。Telomerase-IN-2 具有抗癌作用。
货号:ajcx15500
CAS:1610878-54-0
分子式:C34H39N3O9
分子量：633.69
溶解度:DMSO: 250 mg/mL (394.51 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Telomerase-IN-2 is a telomerase inhibitor, and inhibits telomerase activity by decreasing expression of dyskerin, with an IC50 of 0.89 µM. Anti-cancer activity[1].

[1]. Quan Wang J, et al. Discovery of new chromen-4-one derivatives as telomerase inhibitors through regulating expression of dyskerin. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1199-1211.