MAC13772 是 BioA 酶的有效抑制剂 (IC50=250 nM)，生物素合成的倒数第二步。MAC13772 是一种新型抗菌化合物。
货号:ajcx15634
CAS:4871-40-3
分子式:C8H9N3O3S
分子量：227.24
溶解度:DMSO: 17.86 mg/mL (78.60 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MAC13772 is a potent inhibitor of the enzyme BioA (IC50=250 nM), the antepenultimate step in biotin biosynthesis. MAC13772 is a novel antibacterial compound[1].

[1]. Zlitni S, et al. Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation. Nat Chem Biol. 2013 Dec;9(12):796-804.