HBC514 本身是一种非荧光的 HBC 模拟物，但在与 Pepper RNA 适配体形成紧密复合物后可以发出强烈的绿色荧光，用于 RNA 标记。在活的 Pepper 标记的细胞中，HBC514-Pepper complex 可以使 RNAs 可视化，并且可以通过简单的洗涤和染色灵活地改变荧光。
货号:ajcx16978
CAS:2530161-67-0
分子式:C21H22N4
分子量：330.43
溶解度:DMSO: 25 mg/mL (75.66 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

HBC514 is a nonfluorescent HBC-analog but emits strong green fluorescence upon forming a tight complex with Pepper RNA aptamer. HBC514-Pepper complex enables visualization of RNAs and the fluorescences can be altered flexibly by simple washing and staining in living Pepper-tagged cells[1].

[1]. Chen X, et al. Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs.Nat Biotechnol. 2019 Nov;37(11):1287-1293.