Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst.
货号:ajcx18686
CAS:N/A
分子式:C44H36MnN8 ? 5Cl
分子量：909
溶解度:Soluble at concentration of at least 50mg/mL in 0.1 M Tris-HCI buffer (1 mM EDTA, pH 9.0), and 4mg/mL in PBS (pH 7.2)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. SOD mimetics described to date are unstable and are capable of catalyzing undesired side-reactions in addition to the dismutation of the superoxide radical (O2-). Mn(III)TMPyP is an SOD mimetic with increased stability to pH and hydrogen peroxide. The rate constant for superoxide dismutation and peroxynitrite decomposition are 3.9 x 107 M-1s-1 and ~2 x 106 M-1s-1, respectively. Mn(III)TMPyP protected and enhanced the growth of SOD null E. coli with a doubling time of 60 minutes (as compared to 240 minutes of the control) at 25 &#181M.