Prostaglandin E2 (PGE2) is the major eicosanoid product of cyclooxygenase-1 and 2 in epithelial cells, leukocytes, reproductive tissues, and many others.
货号:ajcx18886
CAS:N/A
分子式:C35H58N4O6S
分子量：662.9
溶解度:DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): .1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Prostaglandin E2 (PGE2) is the major eicosanoid product of cyclooxygenase-1 and 2 in epithelial cells, leukocytes, reproductive tissues, and many others. PGE2 contracts smooth muscle, protects the gastric mucosa, modulates immune function, and regulates fertility and implantation. PGE2 acts through at least four 7-transmembrane G protein-coupled receptors, EP1-EP4. PGE2-biotin is an affinity probe which allows PGE2 to be detected through an interaction with the biotin ligand. PGE2-biotin was designed to allow PGE2 to be detected in complexes with transmembrane receptors and/or nucleic acid or protein binding partners. It is thus a tool to be used in the general elucidation of the mechanism of action of PGs.