Legumain inhibitor 1 是一种有效的选择性的 Legumain 抑制剂，IC50 为 3.6 nM。Legumain inhibitor 1 可用于癌症的研究。
货号:ajcx33974
CAS:2361157-34-6
分子式:C23H25N5O4S
分子量：467.54
溶解度:DMSO : 40 mg/mL (85.55 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Legumain inhibitor 1 is a potent and selective Legumain inhibitor with an IC50 of 3.6 nM. Legumain inhibitor 1 can be used for cancer research[1].

Legumain inhibitor 1 (Compound 16i) shows high microsomal stability with half-life’s in excess of 8 h (mouse and human MICs; CLint >3 µL/min/mg)[1][1].

[1]. Sharon L Eddie, et al. Identification and SAR exploration of a novel series of Legumain inhibitors. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1546-1548.