EGFR-IN-17 是一种有效且选择性的表皮生长因子受体（EGFR）抑制剂（IC50 0.0002 μM），用于克服 C797S 介导的耐药性。
货号:ajcx37732
CAS:N/A
分子式:C27H31ClN7O3P
分子量：568.01
溶解度:DMSO : 12.5 mg/mL (22.01 mM; ultrasonic and warming and heat to 60°C)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

EGFR-IN-17 is a potent and selective inhibitor of the epidermal growth factor receptor ( IC50 0.0002 μM) to overcome C797S-mediated resistance.

[1]. Finlay MRV, et al. Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor to Overcome C797S-Mediated Resistance. J Med Chem. 2021 Sep 23;64(18):13704-13718.