Succinic anhydride 是一种环酐和不可降解的 ADC 连接桥 (ADC linker)，详细信息可参考专利 WO2009064913A1。Succinic anhydride 与专利中的化合物 4 反应，可将前药连接到靶向多肽的胺或羟基 1。
货号:ajcx14492
CAS:108-30-5
分子式:C4H4O3
分子量：100.07
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide[1].

[1]. Dale Boger.et al. Chimer containing a targeting portion linked to a scission-activated duocarmycin-type prodrug. WO2009064913A1.