Pomalidomide-C2-NH2 hydrochloride 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker。
货号:ajcx14720
CAS:2305369-00-8
分子式:C15H17ClN4O4
分子量：352.77
溶解度:DMSO: 125 mg/mL (354.34 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.