15(R)-Prostaglandin I2 (15(R)-PGI2) is an isomer of the natural 15(S) prostanoid, PGI2.
货号:ajcx17796
CAS:N/A
分子式:C20H31O5•Na
分子量：374.5
溶解度:DMF: 5 mg/ml,DMSO: 5 mg/ml,PBS (pH 9.0): >11 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

15(R)-Prostaglandin I2 (15(R)-PGI2) is an isomer of the natural 15(S) prostanoid, PGI2 . PGI2 is an unstable cyclooxygenase metabolite detected first in vascular endothelial cells. It elevates platelet cAMP and is a potent vasodilator and inhibitor of human platelet aggregation with an IC50 value of 5 nM. While the physiological properties of 15(R)-PGI2 are not well known, 15(R) isomers of PGs typically have reduced receptor agonist activity compared to their 15(S) forms.