| 规格: | 98% |
| 分子量: | 450.5 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
Background:
YVAD-CHO is an inhibitor of caspase-1/interleukin-1β converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO . It prevents ICE-like and CPP32-like proteinase activity and inhibits apoptosis induced by ceramide or irinotecan in 4B1 cells when used at a concentration of 600 µM. YVAD-CHO (100 µM) also prevents chromogranin A-induced cell death of primary rat microglia but not primary rat cerebellar granule neurons.
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