CDK ligand for PROTAC hydrochloride 是一种具有抗肿瘤活性的 CDK 抑制剂。CDK ligand for PROTAC hydrochloride 和 CRBN 配体可用于设计 PROTAC CDK4/6 降解剂。
货号:ajcx15582
CAS:N/A
分子式:C25H29ClF2N8O
分子量：531
溶解度:DMSO: 125 mg/mL (235.40 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CDK ligand for PROTAC hydrochloride is a CDK inhibitor with antitumor activity. CDK ligand for PROTAC hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1].

[1]. Nathanael Gray, et al. Degradation of cyclin-dependent kinase 4/6 (cdk4/6) by conjugation of cdk4/6 inhibitors with e3 ligase ligand and methods of use. WO2017185031A1.