AMXT-1501tetrahydrochloride是一种新型的多胺转运系统抑制剂。AMXT1501可阻断免疫活性小鼠中的肿瘤生长，但不能阻断缺乏T细胞无胸腺裸鼠中的肿瘤生长。
货号:ajcx13574
CAS:N/A
分子式:C32H72Cl4N6O2
分子量：714.77
溶解度:H2O : 83.33 mg/mL (116.58 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

AMXT-1501 tetrahydrochloride is a novel inhibitor of the polyamine transport system. AMXT1501 blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells[1]. Polyamine transport[1]

[1]. Hayes CS, et al. Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment. Cancer Immunol Res. 2014 Mar;2(3):274-85.