(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 VH032 的 VHL 配体和 1 个 linker。(S,R,S)-AHPC-C8-NH2 可用于合成靶向 AKT 的 PROTAC 降解剂，例 8，XF038-164A，源于专利文献 WO2019173516A1。
货号:ajcx17306
CAS:2341796-79-8
分子式:C31H47N5O4S
分子量：585.8
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1].

[1]. Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.