| 包装: | 5mg |
| 规格: | 98% |
| 市场价: | 1158元 |
| 分子量: | 464.56 |
Background:
Potent PRDM9 histone methyltransferase inhibitor (IC50 = 85 nM for in vitro methylation of H3K4). Displays >100-fold selectivity over other histone methyltransferases. Inhibits H3K4 methylation in cells (IC50 = 0.8 μM).
Allali-Hassani et al (2019) Discovery of a chemical probe for PRDM9. Nat.Commun. 10 5759 PMID:31848333
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