| 规格: | 98% |
| 分子量: | 409.5 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
Background:
NLRP3 inflammasome inhibitor (IC50 = 574 nM). Inhibits nigericin-induced inflammasome activation in THP-1 cells and Imiquimod induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs).
Baldwin et al (2017) Boron-based inhibitors of the NLRP3 inflammasome. Cell Chem.Biol. 24 1321 PMID:28943355
m.cnreagent.com