AP1867-2-(carboxymethoxy)是一种基于AP1867(一种合成的FKBP12F36V配体)的配体，可通过linker与CRBN配体结合从而形成dTAG分子。
货号:ajcx32372
CAS:2230613-03-1
分子式:C38H47NO11
分子量：693.78
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12F36V-directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules[1].

dTAG molecules engage FKBP12F36V and CRBN[1].

[1]. Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.