ALK2-IN-2 是一种有效的、选择性的活化素受体样激酶 2 (ALK2) 抑制剂，IC50 值为 9 nM，对 ALK2 的抑制作用是 ALK3 的 700 倍。
货号:ajcx39300
CAS:2254409-25-9
分子式:C28H27N5O2S
分子量：497.61
溶解度:DMSO : 125 mg/mL (251.20 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3[1].

[1]. Jiang JK, et al. Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362.