Thalidomide-NH-C6-NH2 TFA是一种合成的 E3 连接酶配体 -linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。
货号:ajcx16768
CAS:2093386-51-5
分子式:C21H25F3N4O6
分子量：486.44
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.