Pomalidomide-PEG3-C2-NH2TFA是一种合成的E3连接酶配体-linker偶联物，包含基于Pomalidomide的cereblon配体和3个单元PEG的linker。
货号:ajcx31328
CAS:2414913-97-4
分子式:C23H29F3N4O9
分子量：562.49
溶解度:DMSO: 100 mg/mL (177.78 mM); Ethanol: 100 mg/mL (177.78 mM); H2O: 16.67 mg/mL (29.64 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

[1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.