Senaparib (IMP4297) 是强效的、选择性的、口服有效的 PARP1/2 抑制剂。Senaparib (IMP4297) 在动物模型中表现强效的抗肿瘤活性。
货号:ajcx33062
CAS:1401682-78-7
分子式:C24H20F2N6O3
分子量：478.45
溶解度:DMSO : 83.33 mg/mL (174.17 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Senaparib (IMP4297) is a highly potent, selective and orally active PARP1/2 inhibitor. Senaparib (IMP4297) exhibits strong antitumor activity in animal models[1].

Senaparib (IMP4297) is under the study for advanced PCa, breast cancer and pancreatic cancer[1].

[1]. P. de Souza, et al. 574P Updated results of phase I study of senaparib (IMP4297) in Australian patients with advanced solid tumours. ABSTRACT ONLY| VOLUME 31, SUPPLEMENT 4, S490, SEPTEMBER 01, 2020.