12-Ethyl-9-hydroxycamptothecin 是 Camptothecin 的衍生物。Camptothecin (CPT) 是一种生物碱，是一种 DNA 拓扑异构酶I (Topo I) 抑制剂，IC50 为 679 nM。
货号:ajcx34354
CAS:119577-28-5
分子式:C22H20N2O5
分子量：392.4
溶解度:DMSO : 83.33 mg/mL (212.36 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1].

12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin.

[1]. Luzzio MJ, et al. Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I. J Med Chem. 1995;38(3):395-401.