Sp-8-CPT-Cyclic AMPS (Sp-8-CPT-cAMPS) is a cell permeable cAMP analog that potently and selectively activates protein kinase A.
货号:ajcx18990
CAS:N/A
分子式:C16H14ClN5O5PS2•Na
分子量：509.9
溶解度:DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 0.5 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Sp-8-CPT-Cyclic AMPS (Sp-8-CPT-cAMPS) is a cell permeable cAMP analog that potently and selectively activates protein kinase A. Sp-8-CPT-cAMPS is a structural combination of the lipophilic and non-hydrolyzable cAMP analogs 8-CPT-Cyclic AMP and Sp-Cyclic AMPS . It is used to investigate the effects of cAMP-dependent PKA signaling. Sp-8-CPT-cAMPS (10 μM; 30 min) reduces the spasmogenic response (pEC50 = 4.74) in guinea-pig trachealis.